Beta-blockers, also called beta-adrenergic blocking agents, are used to treat high blood pressure, abnormal heart rhythms (arrhythmias), chest pain (angina), heart failure, tremors, pheochromocytoma, and hypertrophic subaortic stenosis. Less commonly, beta blockers are used to prevent migraines, or to treat overactive thyroid (hyperthyroidism), anxiety, tremor, and glaucoma (as eyedrops).
Beta blockers work by blocking the neurotransmitters norepinephrine and epinephrine (adrenaline) from binding to beta receptors on nerves. This helps reduce heart rate and lower blood pressure.
Patients who have had a heart attack are usually given beta-blockers because they decrease the chance of having another heart attack or dying of a heart attack. These patients usually take beta-blockers for one year though some may remain on the medication for life.
A patient’s cardiologist will determine if there is additional benefit from staying on beta-blockers or if a patient should be switched to a different class of medication.
What Are Examples of Beta-Blockers?
Examples of beta-blockers include:
- Acebutolol (Sectral)
- Atenolol (Tenormin)
- Betaxolol (Kerlone)
- Bisoprolol fumarate (Zebeta)
- Carteolol hydrochloride (Cartrol)
- Metoprolol tartrate (Lopressor)
- Metoprolol succinate (Toprol-XL)
- Nadolol (Corgard)
- Penbutolol sulfate (Levatol)
- Pindolol (Visken)
- Propranolol hydrochloride (Inderal)
- Solotol hydrochloride (Betapace)
- Timolol maleate (Blocadren)
What Are Side Effects of Beta-Blockers?
Common side effects of beta-blockers include:
- Lightheadedness
- Dizziness
- Tiredness
- Insomnia
- Cold hands and feet
- Depression
- Slow heartbeat
- Impotence
- Symptoms of asthma
Possible long-term side effects of beta-blockers may include:
- Short-term memory loss
- Disorientation for time and place
- Mood swings
- Difficulty concentrating or thinking clearly
- Decreased performance on neuropsychological tests used to measure a psychological function
Serious side effects of beta-blockers include:
From
Heart Health Resources
Image source: iStock Images
United States. American Heart Association. Oct. 31, 2017. "Types of Blood Pressure Medications." http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Types-of-Blood-Pressure-Medications_UCM_303247_Article.jsp#.Wc0x2oprztc
England. National Health Service. July 16, 2019. "Beta blockers." https://www.nhs.uk/conditions/beta-blockers/
https://www.medscape.com/answers/813342-85959/what-are-the-symptoms-of-long-term-beta-blocker-use-in-beta-blocker-toxicity
Sharma, Adhi. MedScape. Oct 21, 2021. "Beta-Blocker Toxicity Clinical Presentation." https://www.acc.org/latest-in-cardiology/articles/2017/01/20/09/36/how-long-should-we-continue-beta-blockers-after-mi