Indigestion (upset stomach or dyspepsia) is a general term that describes a set of gastrointestinal symptoms that happen at the same time, including:
- Pain, burning, or discomfort in the upper abdomen
- Feeling full too soon while eating
- Feeling uncomfortably full after eating
Symptoms of mild indigestion usually only last only a few hours. Most cases of mild indigestion will go away on their own or after making dietary or lifestyle changes. However, indigestion can recur and become chronic in some people.
Indigestion may be:
- Occasional: occurs once in a while
- Chronic: occurs regularly for a few weeks or months
- Functional: chronic symptoms without a specific cause
What Are Symptoms of Indigestion?
Indigestion is not an illness in itself, but it may be a symptom of diseases or conditions of the digestive tract.
Signs of indigestion include:
- Pain, burning, or discomfort in the upper abdomen
- Feeling full too soon while eating
- Feeling uncomfortably full after eating
- Bloating
- Belching
- Burping up food or liquid
- Loud growling or gurgling in the stomach
- Nausea
- Gas
- Heartburn (a separate condition from indigestion)
See a doctor if you have indigestion and:
- It lasts more than 2 weeks
- Swallowing is difficult or painful
- Frequent vomiting
- Bloody vomit
- Black, tar-like stools
- Weight loss without trying
- Pain in the chest, jaw, neck, or arm
- Shortness of breath
- Severe and constant pain in the abdomen
- Sweating
- Yellowing of the eyes or skin (jaundice)
What Causes Indigestion?
Causes of indigestion may include:
- Eating
- Too fast
- Too much
- Spicy, fatty, or greasy foods
- Acidic foods
- Tomatoes and tomato products
- Citrus fruits
- Drinking
- Gastrointestinal conditions
- Acid reflux (GERD)
- Gallbladder inflammation
- Gastritis
- Gastroparesis
- Helicobacter pylori (H. Pylori) infection
- Irritable bowel syndrome (IBS)
- Lactose intolerance
- Peptic ulcer disease
- Stomach cancer
- Smoking
- Some medications
- Certain antibiotics
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve)
- Health problems and digestive tract diseases and conditions can cause indigestion, including
- Psychological factors
How Is Indigestion Diagnosed?
Indigestion is diagnosed with a patient history and physical examination. Tests used to determine the cause of indigestion include:
- Upper GI endoscopy
- Imaging tests
- X-rays
- Computed tomography (CT) scans
- Ultrasound
- H. pylori testing
- Blood
- Stool
- Urea breath tests
- Using an upper GI biopsy
What Is the Treatment for Indigestion?
Treatment for indigestion depends on the cause and may include:
- Medications
- Antacids
- Calcium carbonate (Rolaids, Tums)
- Loperamide (Imodium)
- Simethicone (Maalox, Mylanta)
- Sodium bicarbonate (Alka-Seltzer)
- Antibiotics to treat Helicobacter pylori (H. pylori) infection
- Amoxicillin (Amoxil)
- Clarithromycin (Biaxin)
- Metronidazole (Flagyl)
- Tetracycline (Sumycin)
- Tinidazole (Tindamax)
- H2 blockers to reduce stomach acid production
- Cimetidine (Tagamet HB)
- Famotidine (Pepcid AC)
- Nizatidine (Axid AR)
- Ranitidine (Zantac 75)
- Proton pump inhibitors (PPIs) to treat indigestion along with heartburn
- Esomeprazole (Nexium)
- Lansoprazole (Prevacid)
- Omeprazole (Prilosec, Zegerid)
- Pantoprazole (Protonix)
- Rabeprazole (Aciphex)
- Prokinetics to help the stomach empty faster
- Bethanechol (Urecholine)
- Metoclopramide (Reglan)
- Antacids
- Avoiding foods and beverages that cause indigestion or worsen symptoms
- Psychological therapies
- “Talk therapy” to treat anxiety and depression
- Stress management techniques
- Meditation
- Relaxation exercises
- Counseling
From 
https://www.niddk.nih.gov/health-information/digestive-diseases/indigestion-dyspepsia/definition-facts
https://khealth.com/learn/indigestion/how-long-lasts/