Ovarian cancer is a type of cancer that occurs when cells in the ovaries, the female reproductive glands, become abnormal and grow out of control.
Because ovarian cancer often does not cause symptoms early in the disease, it is often not diagnosed until the later stages. Survival rates are relatively high when the disease is detected early. Overall, about 30% of women live 10 years or more following diagnosis.
A number of factors can affect a woman’s prognosis, such as:
- How early the cancer is detected
- How much the cancer has spread (metastasized)
- The patient’s age
- Overall health
- How well the cancer responds to treatment
Life expectancy for ovarian cancer is often expressed in five-year survival rates, that is, how many people will be alive five years after diagnosis. Survival rates vary depending on the types of ovarian cancer.
Invasive epithelial ovarian cancer five-year survival rates:
- Localized (no sign the cancer has spread outside the ovaries): 92%
- Regional (cancer has spread outside the ovaries to nearby structures or lymph nodes): 76%
- Distant (cancer has spread to distant parts of the body, such as the liver or lungs): 30%
Ovarian stromal tumors five-year survival rates:
- Localized (no sign the cancer has spread outside the ovaries): 98%
- Regional (cancer has spread outside the ovaries to nearby structures or lymph nodes): 89%
- Distant (cancer has spread to distant parts of the body, such as the liver or lungs): 54%
Germ cell tumors of the ovary five-year survival rates:
- Localized (no sign the cancer has spread outside the ovaries): 98%
- Regional (cancer has spread outside the ovaries to nearby structures or lymph nodes): 94%
- Distant (cancer has spread to distant parts of the body, such as the liver or lungs): 74%
What Are Symptoms of Ovarian Cancer?
Early-stage ovarian cancer often does not cause any symptoms.
The most common symptoms of ovarian cancer include:
- Bloating/abdominal distension
- Pelvic or abdominal pain
- Feeling full quickly or after small amounts of food
- Urinary symptoms such as urgency or frequency
Other symptoms of ovarian cancer may include:
- Fatigue
- Upset stomach
- Loss of appetite
- Weight loss
- Back pain
- Pain during intercourse
- Constipation
- Mass felt in the abdomen
- Menstrual changes, such as heavier bleeding than normal or irregular bleeding
How Do You Get an Ovarian Cancer Diagnosis?
Ovarian cancer is usually diagnosed with the following tests:
- Imaging tests:
- Ultrasound
- Computed tomography (CT) scans
- Colonoscopy
- Magnetic resonance imaging (MRI) scans
- Chest X-ray to determine if the cancer has spread (metastasized) to the lungs
- Positron emission tomography (PET) scan
- Barium enema X-ray (not often used)
- Laparoscopy of the pelvis or abdomen
- Biopsy
- Blood tests
- CA-125 test
- Alpha-fetoprotein (AFP)
- Human chorionic gonadotropin (HCG)
- Inhibin
- Lactate dehydrogenase (LDH)
- Estrogen and testosterone
Sometimes doctors will use genetic counseling and genetic testing for certain inherited gene changes for epithelial ovarian cancers.
What Is the Treatment for Ovarian Cancer?
Ovarian cancer is typically treated using one or more of the following:
- Surgery to remove the cancer
- Radiation
- Chemotherapy
- Complementary therapies to treat symptoms such as fatigue, pain, and nausea
- Clinical trials
From
https://www.cancercenter.com/cancer-types/ovarian-cancer/stages
https://pubmed.ncbi.nlm.nih.gov/26244529/