
Benicar HCT (olmesartan medoxomil-hydrochlorothiazide) a combination of olmesartan, an angiotensin II receptor antagonist, and hydrochlorothiazide, a thiazide diuretic (water pill) used to treat high blood pressure (hypertension).
Side effects of Benicar include:
- dizziness or lightheadedness as the body adjusts to the medication,
- headache,
- nausea,
- diarrhea,
- itching,
- skin rash,
- joint or muscle pain,
- back pain,
- stomach/abdominal pain or upset,
- weakness,
- bronchitis,
- flu-like symptoms,
- blood in the urine, and
- sinus infections.
Potentially serious side effects of Benicar include:
- difficulty breathing or swallowing,
- chest pain,
- spinning sensation (vertigo),
- cough,
- high blood potassium (hyperkalemia),
- kidney failure, and
- muscle tissue breakdown (rhabdomyolysis).
What Drugs Interact with Benicar?
Benicar may interact with:
- other blood pressure medications,
- other diuretics,
- steroids,
- aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs),
- lithium,
- cholestyramine or colestipol,
- insulin or oral diabetes medicines,
- barbiturates,
- muscle relaxers, and
- narcotics.
Tell your doctor about all the medications and supplements you use.
From 
Heart Health Resources
References
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021286s040lbl.pdf