What Is Addison’s Disease?
Addison’s disease (primary adrenal insufficiency) is a condition that occurs when the body's adrenal glands do not work normally.
The adrenal glands are small organs located on top of each kidney that produce different hormones: glucocorticoids, mineralocorticoids, and androgens. When the adrenal glands produce fail to produce enough of these hormones, this results in adrenal insufficiency.
What Are Symptoms of Addison’s Disease?
Symptoms of Addison's disease (primary adrenal insufficiency) include:
- Tiredness
- Weakness
- Weight loss
- Loss of appetite
- Darkening of the skin, especially on the face, neck, and back of the hands
- May also appear on scars, skin folds, elbows, knees, knuckles, toes, lips, and mucous membranes such as the inside lining of the cheek
- Nausea
- Vomiting
- Abdominal pain
- Diarrhea
- Low blood pressure on standing or sitting up
- Muscle pain
- Joint pain
- Salt cravings
- Loss of hair from the armpits and pubic area (in women)
- Decreased sex drive (in women)
- Irritability
- Depression
- Low blood sugar (hypoglycemia)
- Irregular or no menstrual periods
When symptoms of Addison's disease become severe and life-threatening, it is called an "adrenal crisis." Adrenal crisis can occur when a person's body is under stress, such as from an infection or injury, or if a person is not taking their medicine regularly.
Symptoms of adrenal crisis include:
- Fever and weakness
- Nausea, vomiting, and stomach pain
- Confusion
- Passing out
- Shock
Adrenal crisis can be a life-threatening condition that requires emergency medical treatment. If you think you are having adrenal crisis, call 9-1-1.
What Should I Eat If I Have Addison's Disease?
People Addison’s disease and have low aldosterone may benefit from a high-sodium diet. Talk to your doctor or a dietitian to determine the proper levels of sodium in the diet.
Treatment for Addison’s disease may include high doses of corticosteroids, which are linked to a higher risk of osteoporosis and bone fracture. People taking corticosteroids should ensure they get adequate calcium and vitamin D.
Examples of calcium-rich foods include:
- Vegetables and fruits
- Collard greens
- Kale
- Soybeans
- Broccoli
- Oranges
- Seafood
- Salmon
- Shrimp
- Sardines
- Dairy products
- Ricotta, part-skim
- Yogurt, plain, low-fat
- Yogurt, Greek
- Skim milk
- Mozzarella, part-skim
- Cheddar cheese
- Cottage cheese
- Fortified foods
- Plant-based milks (e.g. almond, rice, soy), fortified
- Orange juice and other fruit juices, fortified
- Tofu, prepared with calcium
- Oatmeal, fortified
- Cereal, fortified
Examples of foods high in vitamin D include:
- Seafood
- Trout
- Salmon
- Sardines
- Tuna
- Meat and poultry
- Vegetables
- Mushrooms – white and portabella
- Dairy products
- Milk, vitamin D fortified
- Cheddar cheese
- Other
Exposure to sunlight is also another source for vitamin D.